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2013-09-16
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Home Page of Szymon Łęski

I work in the Laboratory of Neuroinformatics, Nencki Institute of Experimental Biology.

I did my PhD (in physics) at the Center for Theoretical Physics.

Research interests

  • development of methods and tools to study local field potentials,
  • current-source density estimation in two and three dimensions,
  • modelling of local field potentials,
  • application of statistical methods to the analysis of neurophysiological data,
  • analysis of behavioral data from IntelliCages and models of learning.

Neuroscience

Publications

  1. S. Łęski, H. Lindén, T. Tetzlaff, K. H. Pettersen, G. T. Einevoll:
    Frequency dependence of signal power and spatial reach of the local field potential,
    PLOS Computational Biology 9 (2013), e1003137,
    preprint: arXiv:1302.4559 [q-bio.NC]
  2. J. Rogala, W. J. Waleszczyk, S. Łęski, A. Wróbel, D. K. Wójcik:
    Reciprocal inhibition and slow calcium decay in perigeniculate interneurons explain changes of spontaneous firing of thalamic cells caused by cortical inactivation, pdf
    Journal of Computational Neuroscience (2012), doi: 10.1007/s10827-012-0430-8,
  3. J. Potworowski, W. Jakuczun, S. Łęski, D. K. Wójcik:
    Kernel Current Source Density Method,
    Neural Computation 24 (2012), 541-575, doi: 10.1162/NECO_a_00236,
    preprint
  4. S. Łęski, K. H. Pettersen, B. Tunstall, G. T. Einevoll, J. Gigg, D. K. Wójcik:
    Inverse Current Source Density method in two dimensions: Inferring neural activation from multielectrode recordings,
    Neuroinformatics 9 (2011), 401-425, doi: 10.1007/s12021-011-9111-4, pdf, MATLAB toolbox (also available through INCF Software Center)
  5. A. Kiryk, G. Mochol, R. K. Filipkowski, M. Wawrzyniak, V. Lioudyno, E. Knapska, T. Gorkiewicz, M. Balcerzyk, S. Łęski, F. Van Leuven, H. P. Lipp, D. K. Wójcik, L. Kaczmarek:
    Cognitive abilities of Alzheimer’s disease transgenic mice are modulated by social context and circadian rhythm,
    Current Alzheimer Research 8 (2011), 883-892
  6. M. J. Hunt, M. Falińska, S. Łęski, D. K. Wójcik, S. Kasicki:
    Differential effects produced by ketamine on oscillatory activity recorded in the rat hippocampus, dorsal striatum and nucleus accumbens,
    Journal of Psychopharmacology 25 (2011), 808–821, doi:10.1177/0269881110362126
  7. S. Łęski, E. Kublik, D. A. Świejkowski, A. Wróbel, D. K. Wójcik:
    Extracting functional components of neural dynamics with Independent Component Analysis and inverse Current Source Density,
    Journal of Computational Neuroscience 29 (2010), 459–473, doi:10.1007/s10827-009-0203-1,
    preprint + supplementary figures, independent component viewer (includes data)
  8. A. Sobolewski, E. Kublik, D. A. Świejkowski, S. Łęski, J. K. Kamiński, A. Wróbel:
    Cross-trial correlation analysis of evoked potentials reveals arousal related attenuation of thalamo-cortical coupling,
    Journal of Computational Neuroscience 29 (2010), 485–493, doi: 10.1007/s10827-010-0220-0, preprint
  9. D. K. Wójcik, S. Łęski:
    Current source density reconstruction from incomplete data, pdf
    Neural Computation 22 (2010), 48–60, arXiv:0903.2379 [q-bio.QM]
  10. S. Łęski, D. K. Wójcik:
    Inferring coupling strength from event-related dynamics, pdf
    Phys. Rev. E 78, 041918 (2008), arXiv:0805.0532v1 [q-bio.NC]
  11. S. Łęski, D. K. Wójcik, J. Tereszczuk, D. A. Świejkowski, E. Kublik, A. Wróbel:
    Inverse Current-Source Density method in 3D: reconstruction fidelity, boundary effects, and influence of distant sources, www
    Neuroinformatics 5 (2007), 207–222

Physics

My PhD thesis (2006) concerned mainly energy-minimizing initial data for two black holes. It also included a part concerning foliations with so-called "rigid spheres" and a chapter devoted to polyhomogeneous (non-smooth on the boundary) solutions to hyperbolic equations. In the thesis I presented an explicit formula for the conformal factor in "Misner initial data".

My MSc thesis (2002) was about the Trautman-Bondi mass (energy of gravitational field measured at null infinity).

Publications

  1. H.-P. Gittel, J. Jezierski, J. Kijowski, S. Łęski:
    Rigid spheres in Riemannian spaces,
    Classical and Quantum Gravity 30, 175010 (2013),
    preprint: arXiv:1206.6216 [gr-qc]
  2. J. Jezierski, J. Kijowski, S. Łęski:
    Energy-minimizing two black holes initial data, pdf
    Phys. Rev. D 76, 024014 (2007), arXiv:0706.0129 [gr-qc]
  3. P.T. Chruściel, S. Łęski:
    Polyhomogeneous solutions of nonlinear wave equations without corner conditions,
    Journal of Hyperbolic Differential Equations 3 (2006), 81–141, math.AP/0506423
  4. S. Łęski:
    Two black hole initial data, pdf
    Phys. Rev. D 71, 124018 (2005), ESI Preprint 1608, gr-qc/0502085
  5. P.T. Chruściel, J. Jezierski, S. Łęski:
    The Trautman-Bondi mass of hyperboloidal initial data sets,
    Adv. Theor. Math. Phys. 8 (2004), 83–139, gr-qc/0307109

Contact

My e-mail is s.leski(at)nenckiOgovOpl
(replace O's with dots).

Mail address is:
Instytut Biologii Doswiadczalnej PAN
ul. Pasteura 3
02-093 Warszawa
Poland